OneNote Is Unable To Start

You might see OneNote failed to start with following error message displayed

OneNote is unable to start. This may be caused by insufficient hard drive space or by insufficient write permissions for OneNote’s notebook cache files in you user setting folder. Try to delete any unnecessary files from your computer and then try starting OneNote again. If this message persists, contact your system administrator. Error code: 0x45D

Solution for OneNote 2007

  1. Open explorer and go to folder %USERPROFILE%AppDataLocalMicrosoftOneNote12.0
  2. Rename OneNoteOfflineCache.onecache to OneNoteOfflineCache.onecache.bak
  3. Start OneNote again.

Note: you might need to mark view hidden files and folders to see the folder in step #1.


May 17 – Some of you ask how to fix this in OneNote 2010 so here is it. For OneNote 2010, change the folder in step #1 to


and the rest steps are same.

12 thoughts on “OneNote Is Unable To Start”

  1. Wow!!!!! Thank you sooooo much! I was just beginning to lose hope. But your fix has solved my issues with one note 2010.

  2. Thank you!!! This definitely worked for OneNote 2010! I was getting nervous because I have my midterms this week and I couldn’t review my notes!

  3. o my goodness thank you so much! theres so many other b-sers out there that ended up me just downloading some stupid stuff that didn’t work. this is legit, and so simple.

  4. I am having the same issue with that error message, but when I change the file “OneNoteOfflineCache.onecache” to .bak, OneNote still does not work. I tried removing those files from that folder all together and restarting the machine as well, but still no luck…I’m running OneNote2007. Any ideas???? I have plenty of hard drive space and permissions on the folder.

  5. I had a similar issue just now, renaming the whole directory 14.0 to 14.0_bak allowed me to bring up onenote. it seemed to rebuild a bunch of things. as far as i can tell, i had one corrupt page. caveat emptor!

  6. See first post PLUS:
    – Right-Click on the file “OneNoteOfflineCache.onecache”. READ_ONLY attributes should be UNCHECKED.
    Good luck!

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